Baseline titer for Widal test in Haryana, India

نویسندگان

  • Seema Mittal
  • Kiran Bala
  • Rajvir Singh
  • Sonia Sharma
چکیده

Enteric fever is a common cause of pyrexia of unknown origin in India and diagnosis of uncomplicated cases based on the signs and symptoms is not specific. Definitive diagnosis of typhoid can be made by the isolation of Salmonella typhi (S.typhi) from blood, faeces or bone marrow. Such culture techniques are often unavailable in developing nation and widal test serves as most efficient serological diagnostic tool in the diagnosis of the enteric fever. It is a tube dilution test which measures agglutinating antibodies against the lipopolysaccharide O and protein flagellar H antigens of S. typhi. There is no consensus regarding diagnostic criteria for interpretation of the test. Classically, a four fold rise of antibody in paired sera 10-14 days apart is considered diagnostic of typhoid fever (Parker, 1984). ISSN: 2319-7706 Volume 3 Number 10 (2014) pp. 93-96 http://www.ijcmas.com

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تاریخ انتشار 2002